Title :
Field stimulation of a three-dimensional bidomain block incorporating rotational anisotropy
Author :
Muzikant, Adam L. ; Henriquez, Craig S.
Author_Institution :
Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
A bidomain model of cardiac tissue was used to examine the effect of anisotropy on field stimulation in two- and three-dimensional myocardium. A two-dimensional tissue sheet (with equal and unequal anisotropy ratios), and a three-dimensional tissue block (with unequal, rotational anisotropy) were placed in a uniform electric field, and the resulting interstitial and transmembrane potentials were computed. Results show that both the interstitial and transmembrane potentials are sensitive to the anisotropy ratios, and that the rotational anisotropy in three-dimensional tissue averages out the effect of the electric field in a manner that may depend on the magnitude of the transmural current redistribution
Keywords :
bioelectric potentials; biological effects of fields; cardiology; physiological models; bidomain model; cardiac tissue; equal anisotropy ratio; field stimulation; interstitial potentials; three-dimensional bidomain block; three-dimensional myocardium; three-dimensional tissue block; transmembrane potentials; transmural current redistribution; two-dimensional myocardium; two-dimensional tissue sheet; unequal anisotropy ratio; unequal rotational anisotropy; uniform electric field; Anisotropic magnetoresistance; Biomedical engineering; Biomembranes; Cardiac tissue; Electrodes; Equations; Myocardium; Optical fiber polarization; Surface resistance; Tensile stress;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.652817
