Title :
Characteristics of activation waves immediately following unsuccessful defibrillation in a computer model of the right atrium
Author :
Ellis, Willard S. ; Lesh, Michael D.
Author_Institution :
Cardiovascular Res. Inst., California Univ., San Francisco, CA, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
Atrial fibrillation is a common disorder associated with significant morbidity and mortality. This study describes a novel computer model designed to simulate defibrillation of the entire right atrium. Six model atria were defibrillated at seven sequential times. Our results indicate that the activation waves propagating immediately following unsuccessful defibrillation occur in cells with exposure to less current during the defibrillation (p<0.0001), and less recovery time following their last activation (p<0.0001)
Keywords :
bioelectric potentials; cardiology; defibrillators; medical computing; physiological models; action potentials; activation waves; arrhythmia; atrial fibrillation; computer model; implantable defibrillator; linearized equations; right atrium; state elements; superexcitability; surviving waves; unsuccessful defibrillation; Atrial fibrillation; Biological system modeling; Cardiology; Computational modeling; Computer simulation; Defibrillation; Electric shock; Heart; Medical treatment; Surgery;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.652820