Title :
Separatopm method of blood constituents using dielectrophoresis and flow-induced shear force
Author :
Yamashita, Masaru ; Miyata, Sumiko ; Takeuchi, Shoji ; Inoue, H.
Author_Institution :
Dept. of Mech. Eng., Keio Univ., Yokohama, Japan
Abstract :
Platelet Rich Plasma (PRP) contains many cytokines for treatment skin diseases. The final goal of this study is to develop the dielectrophoretic PRP purification system enriching the platelets in a label-free manner from whole blood solution. In this study, we characterized dielectrophoretic properties of red blood cell, white blood cell, and platelet for the fundamental study. Moreover, purification of PRP was performed to eliminate red and white blood cells using dielectrophoretic and flow-induced shear force.
Keywords :
bioelectric phenomena; blood; cellular biophysics; electrophoresis; haemodynamics; purification; separation; blood constituent separation method; cytokine; dielectrophoretic PRP purification system; flow-induced shear force; platelet rich plasma; red blood cell; skin disease treatment; white blood cell; Dielectrophoresis; Electrodes; Force; Purification; Red blood cells; White blood cells;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
Conference_Location :
Osaka
DOI :
10.1109/EMBC.2013.6610537