DocumentCode
3204867
Title
Motif detection in protein sequences
Author
Gao, Yuan ; Mathee, Kalai ; Narasimhan, Giri ; Wang, Xuning
Author_Institution
IBM Thomas J. Watson Res. Center, Yorktown Heights, NY, USA
fYear
1999
fDate
1999
Firstpage
63
Lastpage
72
Abstract
We use methods from data mining and knowledge discovery to design an algorithm for detecting motifs in protein sequences. Based on this approach, we have implemented a program called “GYM”. The Helix-Turn-Helix Motif was used as a model system on which to test our program. The program was also extended to detect Homeodomain motifs. The detection results for the two motifs compare favorably with existing programs. In addition, the GYM program provides a lot of useful information about a given protein sequence
Keywords
biology computing; data mining; pattern recognition; proteins; GYM program; Helix-Turn-Helix Motif; Homeodomain motifs; data mining; knowledge discovery; motif detection; protein sequences; Algorithm design and analysis; DNA; Data mining; Design methodology; Displays; Pharmaceuticals; Protein sequence; Sequences; Statistical analysis; System testing;
fLanguage
English
Publisher
ieee
Conference_Titel
String Processing and Information Retrieval Symposium, 1999 and International Workshop on Groupware
Conference_Location
Cancun
Print_ISBN
0-7695-0268-7
Type
conf
DOI
10.1109/SPIRE.1999.796579
Filename
796579
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