Title :
Model development for electrical stimulation of a large number of interacting axons
Author :
Lin, Jim-Cheng ; Durand, Dominique M.
Author_Institution :
Appl. Neural Control Lab., Case Western Reserve Univ., Cleveland, OH, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
A model is presented for studying point source electrical stimulation of a nerve containing a large number of axons. Axons with a given radius distribution are modeled as conducting lines distributed randomly within the nerve. The transmembrane potential can be calculated from a set of linear equations. Both the effect of the individual axon radius on the membrane potential and the contribution of the secondary current sources generated by axons to the membrane potential can be analyzed. The results show that the secondary sources generated by the fiber bundle around an individual axon can significantly affect the transmembrane voltage along its length
Keywords :
bioelectric phenomena; biomembranes; cellular biophysics; neurophysiology; physiological models; electrophysiology; interacting axons interaction; linear equations set; model development; point source electrical stimulation; radius distribution; secondary current sources; transmembrane potential; transmembrane voltage; Biomedical engineering; Biomembranes; Conductivity; Electrical stimulation; Electronic mail; Engine cylinders; Equations; Immune system; Laboratories; Nerve fibers;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.656989
