Title :
Nanodome sensor tubing for monitoring of intravenous drug infusion and metabolites
Author :
Choi, Charles J. ; Wu, Hsin-Yu ; Weyhenmeyer, Jonathan ; George, Sherine ; Cunningham, Brian T.
Author_Institution :
Electr. & Comput. Eng. Dept., Univ. of Illinois at Urbana-Champaign, Urbana, IL, USA
Abstract :
Continuous monitoring of fluids in medical tubing is desired for point-of-care clinical diagnostics. In this work, we incorporate a nanostructured surface-enhanced Raman scattering (SERS) sensor into flexible tubing commonly used for intravenous drug delivery and urinary catheters. We investigate the detection of promethazine (pain medication) and urea (common metabolite found in urine) as model systems for continuous in-line monitoring.
Keywords :
catheters; drug delivery systems; drugs; nanosensors; optical sensors; patient diagnosis; patient monitoring; surface enhanced Raman scattering; SERS; continuous in-line monitoring; flexible tubing; intravenous drug delivery; intravenous drug infusion monitoring; metabolites; nanodome sensor tubing; nanostructured surface-enhanced Raman scattering sensor; pain medication; point-of-care clinical diagnostics; promethazine; urea; urinary catheters; Drugs; Fluids; Monitoring; Raman scattering; Real time systems; Sea measurements; Surface treatment;
Conference_Titel :
Nanotechnology (IEEE-NANO), 2011 11th IEEE Conference on
Conference_Location :
Portland, OR
Print_ISBN :
978-1-4577-1514-3
Electronic_ISBN :
1944-9399
DOI :
10.1109/NANO.2011.6144316
