Fabrication of supported lipid bilayer (SLB) and nanotube transistor hybrid biosensing platform using microfluidic channels

Here we demonstrate a simple way to pattern SLBs onto desired area of carbon nanotube (CNT) films using microfluidic channels. Integrated systems in which all-semiconducting nanotube network transistors are coated directly with lipid bilayers are demonstrated. This new system forms a mechanically robust, stable platform for various sensing applications. Finally, in contrast to all previous studies using nanotubes for membrane interrogation, we use a simple, robust fabrication process based on printable semiconducting nanotube ink, which is compatible with mass-manufacturing in roll-to-roll, flexible electronic applications. This will allow direct translation of the technology into a low cost, next generation measurement system for electrophysiology. This approach will find broad applications in electrophysiology.