Title :
Notice of Retraction
Si multi-nanochannel FETs to improve device uniformity/stability and detection of 10 fM insulin in serum
Author :
Regonda, S. ; Trivedi, K. ; Tian, R. ; Spurgin, L. ; Green, S. ; Jiahuan Ding ; Jinming Gao ; Hu, W.
Author_Institution :
Dept. of Electr. Eng., Univ. of Texas at Dallas, Richardson, TX, USA
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Here we demonstrate the use of multiple Si nanochannel (NC) or nanograting (NG) instead of the conventional single channel or nanowire design in biosensors can significantly reduce device to device variation, and improve device performance (higher current, higher ON/OFF ratio, smaller SS, lower Vt) in buffer solution. NG devices also result in higher sensor stability (repeated sensing over tens of hours) in buffer and human serum. We believe such improvements are due to reduced discrete dopant fluctuation and biochemical noise in the solution. The improved devices allow us to sense pH linearly with 3-aminopropyltriethoxysilane (APTES) coated devices, and to selectively detect insulin with limit of detection down to 10fM in both buffer solution and human serum without pre-purification.
Keywords :
biosensors; elemental semiconductors; field effect transistors; pH measurement; silicon; Si; biochemical noise; biosensors; device stability; device uniformity; insulin; multi nanochannel FET; nanograting; reduced discrete dopant fluctuation; serum; Biosensors; Insulin; Nanobioscience; Nanoscale devices; Performance evaluation; Silicon; Insulin; Si nanograting; bio-FETs; biosensor; pH Sensing;
Conference_Titel :
Nanotechnology (IEEE-NANO), 2011 11th IEEE Conference on
Conference_Location :
Portland, OR
Print_ISBN :
978-1-4577-1514-3
Electronic_ISBN :
1944-9399
DOI :
10.1109/NANO.2011.6144453