DocumentCode :
3227324
Title :
Two feature selections for analysis of microarray data
Author :
Zhang, Yusen ; Ren, Liangyun
Author_Institution :
Sch. of Math. & Stat., Shandong Univ. at Weihai, Weihai, China
fYear :
2010
fDate :
23-26 Sept. 2010
Firstpage :
1259
Lastpage :
1262
Abstract :
Microarray technology allows to measure the expression of thousands of genes simultaneously, and under tens of specific conditions. But the complexity of the data it produced makes it difficult to analyse. So reducing its high dimensionality is useful for both visualization and further clustering of samples. Traditional feature selection methods have various deficiencies. In this paper we propose two novel algorithms based on energy and maximum eigenvalue for feature selection, and test it on the leukemia dataset. we explore the use of support vector machines (SVM) for classification in the microarray analysis. The favorable results we obtained show that our methods for feature selection outperform other methods. At last, Analysis of our results with ROC also shows that our approaches for feature selection perform well.
Keywords :
biology computing; computational complexity; data analysis; data visualisation; feature extraction; genetics; pattern clustering; support vector machines; data complexity; data visualization; feature selection methods; leukemia dataset; microarray data analysis; microarray technology; support vector machines; Bioinformatics; Signal to noise ratio; Support vector machines; SVM; cancer classification; energy; feature selection; maximum eigenvalue; signal noise ratio;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010 IEEE Fifth International Conference on
Conference_Location :
Changsha
Print_ISBN :
978-1-4244-6437-1
Type :
conf
DOI :
10.1109/BICTA.2010.5645082
Filename :
5645082
Link To Document :
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