DocumentCode
3227324
Title
Two feature selections for analysis of microarray data
Author
Zhang, Yusen ; Ren, Liangyun
Author_Institution
Sch. of Math. & Stat., Shandong Univ. at Weihai, Weihai, China
fYear
2010
fDate
23-26 Sept. 2010
Firstpage
1259
Lastpage
1262
Abstract
Microarray technology allows to measure the expression of thousands of genes simultaneously, and under tens of specific conditions. But the complexity of the data it produced makes it difficult to analyse. So reducing its high dimensionality is useful for both visualization and further clustering of samples. Traditional feature selection methods have various deficiencies. In this paper we propose two novel algorithms based on energy and maximum eigenvalue for feature selection, and test it on the leukemia dataset. we explore the use of support vector machines (SVM) for classification in the microarray analysis. The favorable results we obtained show that our methods for feature selection outperform other methods. At last, Analysis of our results with ROC also shows that our approaches for feature selection perform well.
Keywords
biology computing; computational complexity; data analysis; data visualisation; feature extraction; genetics; pattern clustering; support vector machines; data complexity; data visualization; feature selection methods; leukemia dataset; microarray data analysis; microarray technology; support vector machines; Bioinformatics; Signal to noise ratio; Support vector machines; SVM; cancer classification; energy; feature selection; maximum eigenvalue; signal noise ratio;
fLanguage
English
Publisher
ieee
Conference_Titel
Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010 IEEE Fifth International Conference on
Conference_Location
Changsha
Print_ISBN
978-1-4244-6437-1
Type
conf
DOI
10.1109/BICTA.2010.5645082
Filename
5645082
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