DocumentCode :
3228247
Title :
Thyroid volume determination by single photon tomography and 3D processing for activity dose estimation
Author :
Lyra, Maria ; Striligas, John ; Gavrilelli, Maria ; Chatzijiannis, Christos ; Skouroliakou, Katerina
Author_Institution :
Dept. of Radiol., Univ. of Athens, Athens
fYear :
2008
fDate :
10-12 Sept. 2008
Firstpage :
17
Lastpage :
20
Abstract :
This study demonstrates a method of determination of thyroid glandpsilas volume by use of SPECT gamma camera data, in order to calculate thyroidpsilas mass useful in Nuclear medicine therapy. The method consists of the determination of the borders of the gland from a set of transaxial tomographic images by use of a specific for each case threshold value. We have measured the thyroid volume of 48 hyperthyroid patients by adding transaxial slices We analysed the slicespsila data producing interfile format images by Procyon Starlab program and transferring these images in a PC and saved in an uncompressed bitmap format in order to be processed by Interactive Data Language (IDL) tools and Matlab program. Ellipse ROIs are created around each thyroid lobe while rectangular ROIs include both lobes uptake data. Matrices of the maps of the counted voxels of the slices of the organ were created. Their total is multiplied by the elementary voxel size in mm to obtain the final organ volume. Data were extracted and Area, Eccentricity, major & minor axis length, Orientation, equivalent Diameter and Integral Intensity of both left & right lobes were calculated. The delineation procedure adopted in this study was validated by 10 cylindrical phantoms 10 to 100 ml which were imaged under conditions similar to those of the patientspsila studies and by measuring the actual volume of the gland of 3 patients who subsequently underwent thyroidectomy by submersion. The method is simple and fast with a relative error of up to 3% for length, 11% for area and 8% for volume determinations.
Keywords :
biological organs; dosimetry; single photon emission computed tomography; volume measurement; Interactive Data Language tools; Procyon Starlab program; SPECT image; activity dose estimation; lab program; nuclear medicine therapy; single photon tomography; thyroid gland; thyroid lobe; thyroid volume determination; transaxial tomographic images; Cameras; Data analysis; Data mining; Glands; Image analysis; Imaging phantoms; Medical treatment; Nuclear medicine; Single photon emission computed tomography; Volume measurement; 3D thyroid volume; SPECT image; Volume determination in nuclear medicine; medical image measurements;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Imaging Systems and Techniques, 2008. IST 2008. IEEE International Workshop on
Conference_Location :
Crete
Print_ISBN :
978-1-4244-2496-2
Electronic_ISBN :
978-1-4244-2497-9
Type :
conf
DOI :
10.1109/IST.2008.4659932
Filename :
4659932
Link To Document :
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