Liver ablation using a high intensity focused ultrasound system and MRI guidance

Author

Damianou, Christakis ; Ioannides, Kleanthis ; Mylonas, Nicos ; Hadjisavas, Venediktos ; Couppis, Andreas ; Iosif, Dimitris

Author_Institution

Frederick Univ. Cyprus, Nicosia, Cyprus

fYear

2009

fDate

4-7 Nov. 2009

Firstpage

1

Lastpage

4

Abstract

The effectiveness of magnetic resonance imaging (MRI) to monitor thermal lesions created by High Intensity Focused Ultrasound (HIFU) in rabbit liver in vivo is investigated. The MRI sequences of T1-weighted, and T2-weighted fast spin echo (FSE) were evaluated. The main goal in this paper was to find the range of repetition time (TR) and range of echo time (TE) which maximizes the contrast to noise ratio (CNR). An ultrasonic transducer operating at 2 MHz was used, which is navigated using a positioning device. With T1W FSE the range of TR under which CNR is maximized ranges from 400 to 900 ms. The maximum contrast measured is approximately 25. With T2W FSE the range of TE that establishes maximum contrast is between 40 ms and 80 ms, with CNR of approximately 14. T1W FSE is much better than T2W FSE in detecting thermal lesions in liver. Both T1W and T2 W FSE were proven successful to image thermal lesions created by HIFU in rabbit liver in vivo.

Keywords

biomedical MRI; biomedical ultrasonics; liver; radiation therapy; spin echo (NMR); tumours; ultrasonic transducers; HIFU; MRI guidance; T1-weighted fast spin echo; T2-weighted fast spin echo; contrast to noise ratio; frequency 2 MHz; high intensity focused ultrasound system; liver ablation; magnetic resonance imaging; range of echo time; repetition time; thermal lesions; ultrasonic transducer; Focusing; In vivo; Lesions; Liver; Magnetic resonance imaging; Monitoring; Rabbits; Signal to noise ratio; Tellurium; Ultrasonic imaging; HIFU; Liver; MRI; MRI Guidance; Thermal Lesions; Tumors;

fLanguage

English

Publisher

ieee

Conference_Titel

Information Technology and Applications in Biomedicine, 2009. ITAB 2009. 9th International Conference on

Conference_Location

Larnaca

Print_ISBN

978-1-4244-5379-5

Electronic_ISBN

978-1-4244-5379-5

Type

conf

DOI

10.1109/ITAB.2009.5394418

Filename

5394418