• DocumentCode
    3228819
  • Title

    A novel method of recognizing short coding sequences of human genes

  • Author

    Luo, Jiawei ; Yang Li ; Guo, Jiachen

  • Author_Institution
    Sch. of Comput. & Commun., Hunan Univ., Changsha, China
  • fYear
    2010
  • fDate
    23-26 Sept. 2010
  • Firstpage
    152
  • Lastpage
    156
  • Abstract
    In this paper, we present a novel feature representation of DNA sequences based on the graphical representation. Support vector machine (SVM) is applied to classify the coding/non-coding sequence in short human genes. In the process of identifying, we propose an improved self-similar map method to avoid the lack of negative samples sequence. According to the GC content we divide the dataset into several groups and identify these sequences respectively. Finally, the results show that the proposed method obtains a higher accuracy with fewer parameters.
  • Keywords
    DNA; biology computing; data visualisation; support vector machines; DNA sequences; graphical representation; human genes; improved self-similar map; short coding sequences; support vector machine; Bioinformatics; Encoding; Genomics; Informatics; Sensitivity; DNA; coding/non-coding sequence; gene recognition; graphical representation; support vector machine;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010 IEEE Fifth International Conference on
  • Conference_Location
    Changsha
  • Print_ISBN
    978-1-4244-6437-1
  • Type

    conf

  • DOI
    10.1109/BICTA.2010.5645154
  • Filename
    5645154