Title :
Development and testing of nano robot end effector for cell electrophysiology and elastography studies
Author :
Lai, King Wai Chiu ; Gaitas, Angelo ; Xi, Ning ; Yang, Ruiguo ; Fung, Carmen Kar Man
Author_Institution :
Electr. & Comput. Eng. Dept., Michigan State Univ., East Lansing, MI, USA
Abstract :
Electrophysiology and elastrography provide significant information in biological and biomedical studies. Conventional atomic force microscopes (AFMs) have been used for the mechanical characterization of living cells, but they lack the capability to measure the electrical properties of biological cells and tissues. In this work, a novel nano robot end effector has been developed to perform multidimensional measurement of cells. The end effector is designed for characterization of soft materials and it includes an embedded metal electrode for membrane potential measurement of cells.
Keywords :
bioMEMS; bioelectric phenomena; biological techniques; biological tissues; biomechanics; cellular biophysics; elasticity; microrobots; biological cell electrical properties; biological tissue electrical properties; cell elastography studies; cell electrophysiology studies; embedded metal electrode; membrane potential measurement; nanoeffector; nanorobot; soft material characterization; Atomic force microscopy; End effectors; Force; Nanobioscience; USA Councils; atomic force microscopy; elastography; electrophysiology; single cell analysis;
Conference_Titel :
Nanotechnology (IEEE-NANO), 2011 11th IEEE Conference on
Conference_Location :
Portland, OR
Print_ISBN :
978-1-4577-1514-3
Electronic_ISBN :
1944-9399
DOI :
10.1109/NANO.2011.6144645