DocumentCode :
3231407
Title :
Transmural myocardial strain distribution measured at high spatial and temporal resolution
Author :
Thuy Thu Nguyen ; Espinoza, Andreas W. ; Remme, Espen W. ; D´hooge, J. ; Hoff, Lars
Author_Institution :
Fac. of Eng. & Maritime, Vestfold Univ. Coll., Vestfold, Norway
fYear :
2011
fDate :
18-21 Oct. 2011
Firstpage :
696
Lastpage :
699
Abstract :
Most studies of the distribution of radial strain across the left ventricular (LV) wall report increasing strain values from the epi- to the endocardial layer. The aim of this study was to estimate this strain using a novel ultrasound setup. In order to examine the transmural distribution of radial strain in 2 different LV regions, 2 miniature transducers with high temporal and high spatial resolution were directly attached to the heart´s surface in the LV basal and apical region. The myocardium was divided into 5 equally sized layers. Tissue velocities (V) were estimated from the acquired RF signals using a time-delay estimator (TDE) after up-sampling the RF. The initial V estimates were regularized by fitting an active contour through the TDE´s results versus depth. Finally, radial strain rate and strain were calculated resulting in a global motion-compensated assessment of radial strain across the LV wall. The results showed that radial strain increased from the epi- to endocardium in the apical segment while the highest strain values were observed more towards the mid-myocardium near the base. These findings are in agreement with finite element model (FEM) results suggesting that differences in transmural strain distribution could be due to differences in curvature at the base and apex which potentially could explain the conflicting data in the literature.
Keywords :
biological tissues; biomedical measurement; biomedical transducers; biomedical ultrasonics; cardiology; cellular biophysics; finite element analysis; image reconstruction; medical disorders; medical image processing; physiological models; ultrasonic transducers; FEM; LV basal; acquired RF signals; apical region; endocardial layer; endocardium; epicardium; epilayer; finite element model; global motion-compensated assessment; high spatial resolution; high temporal resolution; left ventricular wall report; midmyocardium; miniature transducers; myocardium; radial strain distribution; sized layers; time-delay estimator; tissue velocities; transmural distribution; transmural myocardial strain distribution measurement; transmural strain distribution; ultrasound setup; Heart; Myocardium; Spatial resolution; Strain; Transducers; Ultrasonic imaging; Ultrasonic variables measurement;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Ultrasonics Symposium (IUS), 2011 IEEE International
Conference_Location :
Orlando, FL
ISSN :
1948-5719
Print_ISBN :
978-1-4577-1253-1
Type :
conf
DOI :
10.1109/ULTSYM.2011.0169
Filename :
6293485
Link To Document :
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