• DocumentCode
    3231462
  • Title

    Petri net models and non linear genetic diseases

  • Author

    Glory, P. Persis ; David, N.G. ; Emerald, J.D.

  • Author_Institution
    Dept. of Comput. Applic., Madras Christian Coll., Chennai, India
  • fYear
    2010
  • fDate
    23-26 Sept. 2010
  • Firstpage
    1466
  • Lastpage
    1470
  • Abstract
    Understanding how an individual genetic make-up influences their risk of diseases, is a problem of paramount importance. Although machine-learning techniques are unable to uncover the relationships between genotype and disease, we can still build the best biochemical model automatically with the help of methods that identify the DNA sequence variations in human populations that cause genetic diseases. In this paper, we study Petri net model that is bio chemically plausible to a certain degree, that it may reveal characteristics of the actual biochemical pathways in humans that can aid understanding of the disease.
  • Keywords
    DNA; Petri nets; biochemistry; diseases; genetics; physiological models; DNA sequence variation; Petri net model; biochemical model; biochemical pathway; disease risk; genetic make-up; genotype-disease relationship; human population; nonlinear genetic disease; Biological system modeling; Fires; Petri net; automatic firing of transitions; bio chemical modeling;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010 IEEE Fifth International Conference on
  • Conference_Location
    Changsha
  • Print_ISBN
    978-1-4244-6437-1
  • Type

    conf

  • DOI
    10.1109/BICTA.2010.5645278
  • Filename
    5645278