Title :
The Mathematical Theory of Integrative Physiology: Application to hippocampus for drug discovery
Author :
Bennani, Omar ; Chauvet, Pierre ; Dupont, Jean-Marc
Author_Institution :
CHArt, Ecole Pratique des Hautes Etudes, Paris, France
Abstract :
The modeling and the simulation of biological structure needs a united formalism for all parts of a living system. For this purpose the MTIP (Mathematical Theory of Integrative Physiology) has been developed, by Pr Gilbert Chauvet, to offer an integrated description of a living system. In this paper we will present mainly the passage from a mathematical view of a living subsystem (CA1 circuit of the hippocampus) to its computational implementation and the development of the simulator that goes with in the aim to use and validate the MTIP.
Keywords :
mathematical analysis; pharmaceutical industry; physiological models; CA1 circuit hippocampus; Mathematical Theory of Integrative Physiology; drug discovery; hippocampus; integrative physiology; mathematical theory; Biological system modeling; CA1 circuit; Computing system; Hippocampus; MTIP;
Conference_Titel :
Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010 IEEE Fifth International Conference on
Conference_Location :
Changsha
Print_ISBN :
978-1-4244-6437-1
DOI :
10.1109/BICTA.2010.5645287
