Title :
A Waveguide Biosensors Local Evanescent Field Response to an Immunoassay Complex
Author :
Lear, Kevin L. ; Yuan, Guangwei ; Stephens, Matthew D. ; He, Xinya ; Pownall, Robert ; Yan, Rongjin ; Nikkel, Phil ; Henry, Charles S. ; Chen, Thomas W. ; Dandy, David S.
Author_Institution :
Colorado State Univ., Fort Collins
Abstract :
A compact photonic immunoassay biosensor that can simultaneously sense multiple analytes has been implemented. NSOM results indicate 8% modulation of the local evanescent field due to an 18 nm biological adlayer on the waveguide´s surface.
Keywords :
biosensors; fibre optic sensors; molecular biophysics; near-field scanning optical microscopy; optical planar waveguides; NSOM; biological adlayer; biological molecular probes; immunoassay complex; local evanescent field response; multiple analytes; optical planar waveguide; photonic immunoassay biosensor; size 18 nm; Biomedical optical imaging; Biosensors; Immune system; Optical arrays; Optical microscopy; Optical sensors; Optical surface waves; Optical waveguides; Sensor arrays; Surface waves;
Conference_Titel :
IEEE/LEOS Summer Topical Meetings, 2007 Digest of the
Conference_Location :
Portland, OR
Print_ISBN :
1-4244-0926-8
Electronic_ISBN :
1099-4742
DOI :
10.1109/LEOSST.2007.4288350
