Fabrication of a micro-PCR chip with a heat-sink using TiO2 nano-Fluid

In this paper, a newly-designed micro-PCR chip with a heat-sink using TiO₂ nano-fluid is proposed. The chip consists of three parts; a top part with the micro channel including an integrated heater and sensor, a middle part of the micro chamber that specimens react in, and a bottom part of the micro-fluidic channel that the nano-fluid flows into as the role of a heat-sink. The nano-fluid made use of the TiO₂ material. In order to investigate the heating of a micro chamber, an infrared thermal imaging system measured temperature changes in the chambers.