• DocumentCode
    3235192
  • Title

    Integrated design modeling of miniature syringe for drug delivery

  • Author

    Cao, Dongxing ; Wang, Xiuhong ; Cui, Chunxiang ; Yang, Ge

  • Author_Institution
    Dept. of Mech. Eng., Hebei Univ. of Technol., Tianjin
  • fYear
    2008
  • fDate
    6-9 Jan. 2008
  • Firstpage
    742
  • Lastpage
    746
  • Abstract
    This paper presents a new type of disposable painless syringe using micro-processing technology of MEMS. It designs the overall arrangement of micro needles and a flexible PDMS container with hemisphere shape, describes the behavior of the liquid flow through the needles and integrates design modeling of miniature syringe to explain the phenomena of clog formation. Qualitative analysis and quantitative representation have been carried out about these models. Furthermore the performances of the system and the clog phenomena have been analyzed. This kind of syringe has some great advantages, such as small size, easy to use, storage, transport and distribution. Therefore, it is suit for drug delivery such as insulin, vaccines or antibiotics that do not require exact dosages. The result of simulation has been given to show the availability of design modeling.
  • Keywords
    drug delivery systems; micromechanical devices; MEMS; antibiotics; clog formation; disposable painless syringe; drug delivery; flexible PDMS container; insulin; integrated design modeling; liquid flow; micro needles; microprocessing technology; miniature syringe; qualitative analysis; quantitative representation; vaccines; Containers; Drug delivery; Fluid flow; Insulin; Micromechanical devices; Needles; Performance analysis; Pharmaceutical technology; Shape; Vaccines; MEMS; drug delivery; modeling; syringe;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Nano/Micro Engineered and Molecular Systems, 2008. NEMS 2008. 3rd IEEE International Conference on
  • Conference_Location
    Sanya
  • Print_ISBN
    978-1-4244-1907-4
  • Electronic_ISBN
    978-1-4244-1908-1
  • Type

    conf

  • DOI
    10.1109/NEMS.2008.4484435
  • Filename
    4484435