Title :
Integrated design modeling of miniature syringe for drug delivery
Author :
Cao, Dongxing ; Wang, Xiuhong ; Cui, Chunxiang ; Yang, Ge
Author_Institution :
Dept. of Mech. Eng., Hebei Univ. of Technol., Tianjin
Abstract :
This paper presents a new type of disposable painless syringe using micro-processing technology of MEMS. It designs the overall arrangement of micro needles and a flexible PDMS container with hemisphere shape, describes the behavior of the liquid flow through the needles and integrates design modeling of miniature syringe to explain the phenomena of clog formation. Qualitative analysis and quantitative representation have been carried out about these models. Furthermore the performances of the system and the clog phenomena have been analyzed. This kind of syringe has some great advantages, such as small size, easy to use, storage, transport and distribution. Therefore, it is suit for drug delivery such as insulin, vaccines or antibiotics that do not require exact dosages. The result of simulation has been given to show the availability of design modeling.
Keywords :
drug delivery systems; micromechanical devices; MEMS; antibiotics; clog formation; disposable painless syringe; drug delivery; flexible PDMS container; insulin; integrated design modeling; liquid flow; micro needles; microprocessing technology; miniature syringe; qualitative analysis; quantitative representation; vaccines; Containers; Drug delivery; Fluid flow; Insulin; Micromechanical devices; Needles; Performance analysis; Pharmaceutical technology; Shape; Vaccines; MEMS; drug delivery; modeling; syringe;
Conference_Titel :
Nano/Micro Engineered and Molecular Systems, 2008. NEMS 2008. 3rd IEEE International Conference on
Conference_Location :
Sanya
Print_ISBN :
978-1-4244-1907-4
Electronic_ISBN :
978-1-4244-1908-1
DOI :
10.1109/NEMS.2008.4484435