DocumentCode
3235192
Title
Integrated design modeling of miniature syringe for drug delivery
Author
Cao, Dongxing ; Wang, Xiuhong ; Cui, Chunxiang ; Yang, Ge
Author_Institution
Dept. of Mech. Eng., Hebei Univ. of Technol., Tianjin
fYear
2008
fDate
6-9 Jan. 2008
Firstpage
742
Lastpage
746
Abstract
This paper presents a new type of disposable painless syringe using micro-processing technology of MEMS. It designs the overall arrangement of micro needles and a flexible PDMS container with hemisphere shape, describes the behavior of the liquid flow through the needles and integrates design modeling of miniature syringe to explain the phenomena of clog formation. Qualitative analysis and quantitative representation have been carried out about these models. Furthermore the performances of the system and the clog phenomena have been analyzed. This kind of syringe has some great advantages, such as small size, easy to use, storage, transport and distribution. Therefore, it is suit for drug delivery such as insulin, vaccines or antibiotics that do not require exact dosages. The result of simulation has been given to show the availability of design modeling.
Keywords
drug delivery systems; micromechanical devices; MEMS; antibiotics; clog formation; disposable painless syringe; drug delivery; flexible PDMS container; insulin; integrated design modeling; liquid flow; micro needles; microprocessing technology; miniature syringe; qualitative analysis; quantitative representation; vaccines; Containers; Drug delivery; Fluid flow; Insulin; Micromechanical devices; Needles; Performance analysis; Pharmaceutical technology; Shape; Vaccines; MEMS; drug delivery; modeling; syringe;
fLanguage
English
Publisher
ieee
Conference_Titel
Nano/Micro Engineered and Molecular Systems, 2008. NEMS 2008. 3rd IEEE International Conference on
Conference_Location
Sanya
Print_ISBN
978-1-4244-1907-4
Electronic_ISBN
978-1-4244-1908-1
Type
conf
DOI
10.1109/NEMS.2008.4484435
Filename
4484435
Link To Document