Title :
Compact high-frequency mixing module for microfluidic chips
Author :
Xie, Yan ; Azizi, Farouk ; Mastrangelo, Carlos H.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Case Western Reserve Univ., Cleveland, OH
Abstract :
We present a compact microfluidic mixer module based on high-frequency flow segmentation (HFFS). The module consists of four PDMS valves switched synchronously by high- frequency (-200 Hz) clock signal. The rapid sequential switching of analyte and solvent plugs produces a high degree of mixing (0.8) within a short (1 mm) flow distance in very small (3 mm2) module footprint making such module suitable for large-scale integration in microfluidic chips.
Keywords :
microfluidics; mixers (circuits); PDMS valve; clock signal; flow segmentation; high-frequency mixing module; large-scale integration; microfluidic chips; Boundary conditions; Clocks; Frequency; Lab-on-a-chip; Microfluidics; Plugs; Solvents; Systems engineering and theory; USA Councils; Valves; Taylor dispersion mixing; high-frequency flow segmentation (HFFS);
Conference_Titel :
Nano/Micro Engineered and Molecular Systems, 2008. NEMS 2008. 3rd IEEE International Conference on
Conference_Location :
Sanya
Print_ISBN :
978-1-4244-1907-4
Electronic_ISBN :
978-1-4244-1908-1
DOI :
10.1109/NEMS.2008.4484472
