Spectral Analysis of DNA Sequence: The Exon´s Location Method

The system´s analysis concepts based on signal processing methods are considered as very important tools in the genomic field´s exploration. Spectral analysis of DNA sequences reveals genome´s specific periodicities. Studying one organism´s genome requires three steps. First, the DNA coding method: the DNA´s string data are transformed into numerical signal. Second periodicities are detected by spectral analysis. Third, following the evolution of this periodicity along the genome allows the exon´s, or protein coding region´s, location. In this paper, we expose the exon´s location method: including the coding and spectral analysis steps. After, we propose a two dimensional graphical representation for the spectrum. The experimental result including a variety of coding indicator´s methods reveals the importance of each base´s combination, from one base to four group bases, in the exon´s enhancement. The contributions in percent of each of this group´s indicator are finally estimated.