Title :
Novel Front-End Circuit Architectures for Integrated Bio-Electronic Interfaces
Author :
Guiducci, Carlotta ; Schmid, Alexandre ; Gurkaynak, Frank K. ; Leblebici, Yusuf
Author_Institution :
DEIS, Univ. of Bologna, Bologna
Abstract :
The prospective use of upcoming nanometer CMOS technology nodes (65 nm, 45 nm, and beyond) in bio-electronic interfaces is raising a number of important issues concerning circuit architectures and design. In particular, the advantages of scaling and higher density integration must be balanced against the requirements of low noise design, uniform power density and surface temperature distribution, better component matching, and immunity to parameter variations. Dealing with these constraints also requires more innovative approaches towards hybrid integration technologies. In this paper, we discuss the key design issues with specific examples from DNA detection, protein detection, and neuro-electronic interfaces.
Keywords :
CMOS integrated circuits; biomedical electronics; biosensors; integrated circuit design; temperature distribution; DNA detection; circuit design; component matching; front-end circuit architectures; hybrid integration technologies; integrated bio-electronic interfaces; low noise design; nanometer CMOS technology nodes; neuro-electronic interfaces; parameter variations; protein detection; surface temperature distribution; uniform power density; Biological materials; Biological systems; Biosensors; CMOS technology; Chemical elements; Fabrication; Integrated circuit technology; Laboratories; Nanobioscience; Temperature sensors;
Conference_Titel :
Design, Automation and Test in Europe, 2008. DATE '08
Conference_Location :
Munich
Print_ISBN :
978-3-9810801-3-1
Electronic_ISBN :
978-3-9810801-4-8
DOI :
10.1109/DATE.2008.4484863
