Novel Front-End Circuit Architectures for Integrated Bio-Electronic Interfaces

Author

Guiducci, Carlotta ; Schmid, Alexandre ; Gurkaynak, Frank K. ; Leblebici, Yusuf

Author_Institution

DEIS, Univ. of Bologna, Bologna

fYear

2008

fDate

10-14 March 2008

Firstpage

1328

Lastpage

1333

Abstract

The prospective use of upcoming nanometer CMOS technology nodes (65 nm, 45 nm, and beyond) in bio-electronic interfaces is raising a number of important issues concerning circuit architectures and design. In particular, the advantages of scaling and higher density integration must be balanced against the requirements of low noise design, uniform power density and surface temperature distribution, better component matching, and immunity to parameter variations. Dealing with these constraints also requires more innovative approaches towards hybrid integration technologies. In this paper, we discuss the key design issues with specific examples from DNA detection, protein detection, and neuro-electronic interfaces.

Keywords

CMOS integrated circuits; biomedical electronics; biosensors; integrated circuit design; temperature distribution; DNA detection; circuit design; component matching; front-end circuit architectures; hybrid integration technologies; integrated bio-electronic interfaces; low noise design; nanometer CMOS technology nodes; neuro-electronic interfaces; parameter variations; protein detection; surface temperature distribution; uniform power density; Biological materials; Biological systems; Biosensors; CMOS technology; Chemical elements; Fabrication; Integrated circuit technology; Laboratories; Nanobioscience; Temperature sensors;

fLanguage

English

Publisher

ieee

Conference_Titel

Design, Automation and Test in Europe, 2008. DATE '08

Conference_Location

Munich

Print_ISBN

978-3-9810801-3-1

Electronic_ISBN

978-3-9810801-4-8

Type

conf

DOI

10.1109/DATE.2008.4484863

Filename

4484863