Title :
A modified Marriage in Honey Bee Optimisation (MBO) algorithm for protein structure prediction
Author :
Bahamish, Hesham Awadh A ; Abdullah, Rosni ; Abu-Hashem, Muhannad A.
Author_Institution :
Sch. of Comput. Sci., Univ. Sains Malaysia, Pinang, Malaysia
Abstract :
This paper refines and introduces a modification to the Marriage in Honey Bee Optimisation algorithm (MBO). The modified algorithm was applied to predict the structure of Met-enkphaline using torsion angles representation and ECEPP/3 energy function. The results showed the significance of the modification. The algorithm was able to find the lowest reported free energy conformation of value -12.43 kcal/mol.
Keywords :
biology computing; optimisation; proteins; ECEPP/3 energy function; Met-enkphaline; marriage in honey bee optimisation algorithm; protein structure prediction; torsion angles representation; Computational modeling; Computers; Optimization; Particle swarm optimization; Prediction algorithms; Proteins; Silicon; Swarm intelligence; optimisation algorithms; tertiary structure; torsion angles;
Conference_Titel :
Computer Technology and Development (ICCTD), 2010 2nd International Conference on
Conference_Location :
Cairo
Print_ISBN :
978-1-4244-8844-5
Electronic_ISBN :
978-1-4244-8845-2
DOI :
10.1109/ICCTD.2010.5646067
