Title : 
Bits and Bases: An Analysis of Genetic Information Paradigms
         
        
            Author : 
May, Elebeoba E.
         
        
            Author_Institution : 
Sandia Nat. Labs., Albuquerque
         
        
        
        
        
        
            Abstract : 
The objective of this work is to form a general understanding of biological communication mechanisms by applying Shannon information theory and coding theory concepts to study the complex system of information transmission in biological organisms. We assess the viability of a biological coding theory framework by exploring coding theoretic characteristics of the genetic system that parallel traditional communication systems. We present results of channel capacity studies for prokaryotic and eukaryotic replication processes and explore connections between capacity and cellular aging.
         
        
            Keywords : 
channel capacity; information theory; Shannon information theory; biological coding theory framework; biological communication mechanisms; coding theory concepts; genetic information paradigms; information transmission; Biological information theory; Biological systems; Codes; Communication systems; DNA; Error correction; Genetics; Information analysis; Proteins; Sequences; biological coding theory; channel capacity; genetic information; mutation;
         
        
        
        
            Conference_Titel : 
Signals, Systems and Computers, 2007. ACSSC 2007. Conference Record of the Forty-First Asilomar Conference on
         
        
            Conference_Location : 
Pacific Grove, CA
         
        
        
            Print_ISBN : 
978-1-4244-2109-1
         
        
            Electronic_ISBN : 
1058-6393
         
        
        
            DOI : 
10.1109/ACSSC.2007.4487187