Medical magnetic source imaging

Magnetoencephalography, the detection of extracranial magnetic fields arising from intracranial neuronal activity, provides a powerful new technique in the mapping of the human brain function. In combination with high resolution MRI, as magnetic source images (MSI), it provides a tool for clinical practice as well as neuroscience research. Detection of evoked and spontaneous electrical activity extends the range of applications to include particularly the localization of sources of epileptogenic activity. Confirmation with intra-operative mapping and correlation with ether noninvasive modalities indicate the efficacy of the method. In summary, the combination of high temporal resolution (milliseconds) and good spatial resolution (millimeters) suggest that MSI may offer new insights into brain functional organization and activity