DocumentCode
3250634
Title
Using evolutionary algorithms to estimate transition rates of discrete characteristics in phylogenetic trees
Author
Meade, Andrew ; Corne, David ; Pagel, Mark ; Sibly, Richard
Author_Institution
Sch. of Comput. Sci., Reading Univ., UK
Volume
2
fYear
2001
fDate
2001
Firstpage
1170
Abstract
Phylogenetics is the study of evolutionary relationships between and among species or individuals, and involves the construction and analysis of evolutionary trees. In particular, certain questions frequently arise which can be examined by analysing a tree in terms of maximum likelihood with respect to a particular characteristic or set of characteristics. An important concept in these respects is the `transition rate´ between two states of a character over evolutionary time. Various analyses based on given phylogenetic trees involve a search for a set of transition rates which maximise the likelihood of the given tree. We investigate the preliminary use of an evolutionary algorithm for this search problem, and find that it seems significantly superior to the existing method (a conjugate-gradient search) used in the evolutionary biology community for this purpose. Our test case is drawn from the field of evolutionary linguistics, emphasising the broad applicability of this search problem
Keywords
computational linguistics; evolutionary computation; genetics; maximum likelihood estimation; search problems; trees (mathematics); conjugate-gradient search; discrete characteristics; evolutionary algorithms; evolutionary biology community; evolutionary linguistics; evolutionary relationships; evolutionary time; evolutionary trees; maximum likelihood; phylogenetic trees; phylogenetics; search problem; test case; transition rate; transition rate estimation; transition rates; Animals; DNA; Evolution (biology); Evolutionary computation; Humans; Maximum likelihood estimation; Phylogeny; Search problems; Sequences; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Evolutionary Computation, 2001. Proceedings of the 2001 Congress on
Conference_Location
Seoul
Print_ISBN
0-7803-6657-3
Type
conf
DOI
10.1109/CEC.2001.934323
Filename
934323
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