• DocumentCode
    3250634
  • Title

    Using evolutionary algorithms to estimate transition rates of discrete characteristics in phylogenetic trees

  • Author

    Meade, Andrew ; Corne, David ; Pagel, Mark ; Sibly, Richard

  • Author_Institution
    Sch. of Comput. Sci., Reading Univ., UK
  • Volume
    2
  • fYear
    2001
  • fDate
    2001
  • Firstpage
    1170
  • Abstract
    Phylogenetics is the study of evolutionary relationships between and among species or individuals, and involves the construction and analysis of evolutionary trees. In particular, certain questions frequently arise which can be examined by analysing a tree in terms of maximum likelihood with respect to a particular characteristic or set of characteristics. An important concept in these respects is the `transition rate´ between two states of a character over evolutionary time. Various analyses based on given phylogenetic trees involve a search for a set of transition rates which maximise the likelihood of the given tree. We investigate the preliminary use of an evolutionary algorithm for this search problem, and find that it seems significantly superior to the existing method (a conjugate-gradient search) used in the evolutionary biology community for this purpose. Our test case is drawn from the field of evolutionary linguistics, emphasising the broad applicability of this search problem
  • Keywords
    computational linguistics; evolutionary computation; genetics; maximum likelihood estimation; search problems; trees (mathematics); conjugate-gradient search; discrete characteristics; evolutionary algorithms; evolutionary biology community; evolutionary linguistics; evolutionary relationships; evolutionary time; evolutionary trees; maximum likelihood; phylogenetic trees; phylogenetics; search problem; test case; transition rate; transition rate estimation; transition rates; Animals; DNA; Evolution (biology); Evolutionary computation; Humans; Maximum likelihood estimation; Phylogeny; Search problems; Sequences; Testing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2001. Proceedings of the 2001 Congress on
  • Conference_Location
    Seoul
  • Print_ISBN
    0-7803-6657-3
  • Type

    conf

  • DOI
    10.1109/CEC.2001.934323
  • Filename
    934323