Contractile force measurement of cardiomyocytes using a hybrid biopolymer microcantilever array

This paper reports a method for quantitative and real-time contractile force measurement of cardiomyocytes using a hybrid biopolymer micracrocantilever array. We designed and fabricated a hybrid biopolymer microcantilever array made of PDMS (polydimethylsiloxane) elastomer to overcome the above problems. Culturing primary cardiomyocytes on PDMS microcantilever array leads to self-organization of cells on the structure, which enables to make massively paralleled arrangement of cells in the hybrid system.