DocumentCode
3274812
Title
The THz dance of the protein with the water
Author
Havenith, M. ; Leitner, D. ; Gruebele, M.
Author_Institution
Dept. of Phys. Chem. II, Ruhr-Univ. Bochum, Bochum
fYear
2008
fDate
15-19 Sept. 2008
Firstpage
1
Lastpage
1
Abstract
We show that THz absorption measurements of solvated proteins is a new tool to probe the dynamical hydration shell around biomolecules. The measurement of the concentration dependent changes of the Terahertz absorption coefficient yields information on the solute induced changes of the solvation dynamics, its dependence on protein concentration, and the width of the dynamic hydration layer. The results show the potential of THz spectroscopy to yield answers on these biologically relevant questions.
Keywords
absorption coefficients; biochemistry; molecular biophysics; proteins; solvation; submillimetre wave spectra; THz spectroscopy; biomolecules; dynamical hydration shell; solvated proteins; solvation dynamics; terahertz absorption coefficient measurements; water; Absorption; Chemistry; Computational biology; Molecular biophysics; Presence network agents; Probes; Proteins; Solvents; Spectroscopy; Submillimeter wave measurements;
fLanguage
English
Publisher
ieee
Conference_Titel
Infrared, Millimeter and Terahertz Waves, 2008. IRMMW-THz 2008. 33rd International Conference on
Conference_Location
Pasadena, CA
Print_ISBN
978-1-4244-2119-0
Electronic_ISBN
978-1-4244-2120-6
Type
conf
DOI
10.1109/ICIMW.2008.4665536
Filename
4665536
Link To Document