Capacitance change estimation for an immunosensor chip

This paper addresses the capacitance estimation for an immunosensor chip (ISC). It is known that the capacitance of an antibody, or other ligand such as an scFv molecule, changes when it binds with an antigen. If the sensor plane of the ISC is coated with an array of a specific receptor or ligand that binds to the protein on the virus, then the diseased cells can be detected, captured, and dealt with accordingly. This detection can be carried out by measuring the change in capacitance upon binding. In order to develop models for this capacitance change, we use capacitance static electrical methods.