Title :
The effects of formalin fixing on terahertz properties of biological samples
Author :
Sun, Yiwen ; Pickwell-MacPherson, Emma
Author_Institution :
Dept. of Electron. Eng., Chinese Univ. of Hong Kong, Hong Kong
Abstract :
Terahertz radiation is sensitive to covalently cross-linked proteins and can be used to probe unique spectroscopic signatures. In this paper we demonstrate how the terahertz properties of tissue are affected by formalin fixing. We study the detailed changes arising from different fixation times and see that formalin fixing reduces the refractive index and the absorption coefficient of our samples in the terahertz regime.
Keywords :
absorption coefficients; biological effects of microwaves; biological tissues; molecular biophysics; molecular configurations; proteins; refractive index; terahertz wave spectra; absorption coefficient; biological samples; covalently cross-linked proteins; formalin fixing; refractive index; terahertz radiation; tissue; Biomedical optical imaging; Frequency; Optical pulses; Optical refraction; Optical sensors; Optical variables control; Proteins; Refractive index; Spectroscopy; Ultrafast optics;
Conference_Titel :
Infrared, Millimeter and Terahertz Waves, 2008. IRMMW-THz 2008. 33rd International Conference on
Conference_Location :
Pasadena, CA
Print_ISBN :
978-1-4244-2119-0
Electronic_ISBN :
978-1-4244-2120-6
DOI :
10.1109/ICIMW.2008.4665719
