Title :
Implantable optical sensor for continuous monitoring of various hemoglobin derivatives and tissue perfusion
Author :
Fiala, Jens ; Gehrke, Robert ; Weber, Niklas ; Bingger, Philipp ; Zappe, Hans ; Seifert, Andreas
Author_Institution :
Dept. of Microsyst. Eng. (IMTEK), Univ. of Freiburg, Freiburg, Germany
Abstract :
A novel implantable optical sensor for continuous long-term monitoring of arterial oxygen saturation and monitoring of tissue perfusion is introduced. The photoplethysmo-graphic multi-wavelength sensor with optoelectronic components mounted onto a flexible substrate and encapsulated in biocompatible silicone is attached to well-perfused intrathoracic tissue or directly onto organ surfaces. A proof-of-principle could be shown by first measurements carried out on custom-developed artificial tissue and by in vivo finger-tip measurements as well as in a domestic pig.
Keywords :
biochemistry; biological organs; biological tissues; biomedical equipment; blood vessels; encapsulation; gas sensors; haemorheology; molecular biophysics; optical sensors; optoelectronic devices; oxygen; patient monitoring; plethysmography; proteins; silicones; O2; arterial oxygen saturation; continuous monitoring; custom-developed artificial tissue; encapsulation; hemoglobin derivatives; implantable optical sensor; intrathoracic tissue; optoelectronic components; photoplethysmographic multiwavelength sensor; proof-of-principle; silicone; tissue perfusion; Biosensors; Blood vessels; Cardiovascular diseases; Mechanical sensors; Monitoring; Optical sensors; Photodetectors; Photodiodes; Probes; Pulse measurements;
Conference_Titel :
Sensors, 2009 IEEE
Conference_Location :
Christchurch
Print_ISBN :
978-1-4244-4548-6
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2009.5398324
