Impedance based electrochemical biosensors

Author

Narakathu, Binu Baby ; Bejcek, Bruce E. ; Atashbar, Massood Z.

Author_Institution

Dept. of Electr. & Comput. Eng., Western Michigan Univ., Kalamazoo, MI, USA

fYear

2009

fDate

25-28 Oct. 2009

Firstpage

1212

Lastpage

1216

Abstract

An impedance based electrochemical biosensor was designed and fabricated for the detection of various chemical and biological species, with glass as substrate material and gold electrodes. A flow cell with inlet and outlet ports for the micro fluidic chamber was designed and fabricated using an acrylic material with a reservoir volume of 78 Â¿l. The feasibility of the fabricated sensor for detecting very low concentration of chemical and biological species was demonstrated. The impedance based response of the two-terminal device revealed a very high sensitivity with low concentrations of potassium chloride (KCl), cadmium sulphide (CdS), mouse monoclonal IgG, and D-proline at pico mole levels.

Keywords

bioMEMS; biological techniques; electric impedance; electrochemical electrodes; electrochemical sensors; microfluidics; CdS; D-proline; KCl; acrylic material; cadmium sulphide; electrochemical biosensors; flow cell; glass substrate; gold electrodes; impedance based sensor; microfluidic chamber; mouse monoclonal IgG; potassium chloride; Biological materials; Biosensors; Chemical and biological sensors; Electrodes; Fluidic microsystems; Glass; Gold; Impedance; Microfluidics; Reservoirs;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2009 IEEE

Conference_Location

Christchurch

ISSN

1930-0395

Print_ISBN

978-1-4244-4548-6

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2009.5398365

Filename

5398365