Title :
Impedance based electrochemical biosensors
Author :
Narakathu, Binu Baby ; Bejcek, Bruce E. ; Atashbar, Massood Z.
Author_Institution :
Dept. of Electr. & Comput. Eng., Western Michigan Univ., Kalamazoo, MI, USA
Abstract :
An impedance based electrochemical biosensor was designed and fabricated for the detection of various chemical and biological species, with glass as substrate material and gold electrodes. A flow cell with inlet and outlet ports for the micro fluidic chamber was designed and fabricated using an acrylic material with a reservoir volume of 78 ¿l. The feasibility of the fabricated sensor for detecting very low concentration of chemical and biological species was demonstrated. The impedance based response of the two-terminal device revealed a very high sensitivity with low concentrations of potassium chloride (KCl), cadmium sulphide (CdS), mouse monoclonal IgG, and D-proline at pico mole levels.
Keywords :
bioMEMS; biological techniques; electric impedance; electrochemical electrodes; electrochemical sensors; microfluidics; CdS; D-proline; KCl; acrylic material; cadmium sulphide; electrochemical biosensors; flow cell; glass substrate; gold electrodes; impedance based sensor; microfluidic chamber; mouse monoclonal IgG; potassium chloride; Biological materials; Biosensors; Chemical and biological sensors; Electrodes; Fluidic microsystems; Glass; Gold; Impedance; Microfluidics; Reservoirs;
Conference_Titel :
Sensors, 2009 IEEE
Conference_Location :
Christchurch
Print_ISBN :
978-1-4244-4548-6
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2009.5398365
