Accelerated surface plasmon resonance biosensing by surface acoustic waves microstreaming

Author

Renaudin, Alan ; Chabot, Vincent ; Grondin, Etienne ; Aimez, Vincent ; Charette, Paul G.

Author_Institution

Centre de Rech. en Nanofabrication et Nanocaracterisation, Univ. de Sherbrooke, Sherbrooke, QC, Canada

fYear

2011

fDate

20-23 Feb. 2011

Firstpage

1140

Lastpage

1143

Abstract

This paper describes our design incorporating surface plasmon resonance biosensing and surface acoustic wave active microfluidic mixing, integrated on a single LiNbO₃ piezoelectric substrate. Validation experiments show that surface acoustic wave-induced microstreaming results in significant accelerated binding kinetics in a case of a standard avidin-biotin affinity assay.

Keywords

bioMEMS; biosensors; microfluidics; microsensors; piezoelectric devices; surface acoustic wave transducers; surface plasmon resonance; LiNbO₃; accelerated surface plasmon resonance biosensing; binding kinetics; piezoelectric substrate; standard avidin-biotin affinity assay; surface acoustic wave active microfluidic mixing; surface acoustic wave-induced microstreaming; Biosensors; Microfluidics; Optical surface waves; Plasmons; Reflectivity; Substrates; Surface acoustic waves; Binding Kinetics; Biosensing; Streaming; Surface Acoustic Waves; Surface Plasmon Resonance;

fLanguage

English

Publisher

ieee

Conference_Titel

Nano/Micro Engineered and Molecular Systems (NEMS), 2011 IEEE International Conference on

Conference_Location

Kaohsiung

Print_ISBN

978-1-61284-775-7

Type

conf

DOI

10.1109/NEMS.2011.6017558

Filename

6017558