Title :
Accelerated surface plasmon resonance biosensing by surface acoustic waves microstreaming
Author :
Renaudin, Alan ; Chabot, Vincent ; Grondin, Etienne ; Aimez, Vincent ; Charette, Paul G.
Author_Institution :
Centre de Rech. en Nanofabrication et Nanocaracterisation, Univ. de Sherbrooke, Sherbrooke, QC, Canada
Abstract :
This paper describes our design incorporating surface plasmon resonance biosensing and surface acoustic wave active microfluidic mixing, integrated on a single LiNbO3 piezoelectric substrate. Validation experiments show that surface acoustic wave-induced microstreaming results in significant accelerated binding kinetics in a case of a standard avidin-biotin affinity assay.
Keywords :
bioMEMS; biosensors; microfluidics; microsensors; piezoelectric devices; surface acoustic wave transducers; surface plasmon resonance; LiNbO3; accelerated surface plasmon resonance biosensing; binding kinetics; piezoelectric substrate; standard avidin-biotin affinity assay; surface acoustic wave active microfluidic mixing; surface acoustic wave-induced microstreaming; Biosensors; Microfluidics; Optical surface waves; Plasmons; Reflectivity; Substrates; Surface acoustic waves; Binding Kinetics; Biosensing; Streaming; Surface Acoustic Waves; Surface Plasmon Resonance;
Conference_Titel :
Nano/Micro Engineered and Molecular Systems (NEMS), 2011 IEEE International Conference on
Conference_Location :
Kaohsiung
Print_ISBN :
978-1-61284-775-7
DOI :
10.1109/NEMS.2011.6017558
