Title :
Rapid cholesterol detection by functionalized carbon nanotube based electrochemical sensor on flow injection microfluidic chip
Author :
Wisitsoraat, A. ; Sritongkham, P. ; Karuwan, C. ; Phokharatkul, D. ; Maturos, T. ; Tuantranont, A.
Author_Institution :
Nat. Electron. & Comput. Technol. Center, Pathumthani, Thailand
Abstract :
In this work, CNTs electrochemical electrode has been integrated on a flow injection based microfluidic chip for detection of cholesterol (CHO). Metal electrodes were deposited and CNTs were grown on a glass substrate by sputtering and chemical vapor deposition at low temperature. Polydimethylsiloxane microfluidic componet was then bonded on substrate. Cholesterol oxidase/potassium hexacyanoferrate were immobilized by polyvinyl alcohol using in-channel flow processing. Cholesterol detections were made by flow injection analysis and fast response time and high sensitivity have been achieved with high throughput of more than 100 samples per hour.
Keywords :
bioMEMS; biochemistry; biomedical electrodes; biomedical measurement; carbon nanotubes; electrochemical electrodes; electrochemical sensors; lab-on-a-chip; microfluidics; nanotube devices; polymers; C; CNT electrochemical electrode; carbon nanotube; chemical vapor deposition; cholesterol oxidase; flow injection microfluidic chip; functionalised CNT based electrochemical sensor; in channel flow processing; metal electrodes; polydimethylsiloxane microfluidic component; polyvinyl alcohol; potassium hexacyanoferrate; rapid cholesterol detection; sputtering; Bonding; Carbon nanotubes; Chemical sensors; Chemical vapor deposition; Delay; Electrodes; Glass; Microfluidics; Sputtering; Temperature sensors;
Conference_Titel :
Sensors, 2009 IEEE
Conference_Location :
Christchurch
Print_ISBN :
978-1-4244-4548-6
Electronic_ISBN :
1930-0395
DOI :
10.1109/ICSENS.2009.5398459
