DocumentCode :
3295347
Title :
Live cell index sensing based on the reflection mode of tilted fiber tip with gold nanoparticles
Author :
Guanghui Wang ; Xinting Zheng ; Shum, P.P. ; Changming Li ; Ho-Pui Ho ; Limin Tong
Author_Institution :
Network Technol. Res. Centre, Nanyang Technol. Univ., Singapore, Singapore
fYear :
2010
fDate :
24-27 Oct. 2010
Firstpage :
116
Lastpage :
119
Abstract :
We presented a micrometer size tapered fiber tip for real-time refractive index measurement of live cell. The tip is cut with a specific tilted angle. Only the cutting surface of tip apex is coated with gold nanoparticles (GNPs) by selective bonding method. The evanescent wave at the apex will excite the localized surface plasmon resonance (LSPR) of GNPs. With enhanced scattering at the resonance wavelength, the tip reflection will experience a loss, which is analogous to attenuated total reflection (ATR). By measure the reflection beam, a wavelength dependent loss dip in the reflection spectrum or an intensity loss of a specific wavelength could be used to detect the refractive index of live cell.
Keywords :
biomedical measurement; biomedical optical imaging; biosensors; cellular biophysics; coatings; gold; nanobiotechnology; nanoparticles; refractive index; refractive index measurement; surface plasmon resonance; LSPR; attenuated total reflection; cutting surface; evanescent wave; gold nanoparticles; live cell index sensing; localized surface plasmon resonance; micrometer size tapered fiber tip; real-time refractive index measurement; reflection mode; selective bonding method; tilted fiber tip; tip apex coating; Gold nanoparticles (GNPs); Index sensing; Localized surface plasmon resonance (LSPR); Tilted fiber tip;
fLanguage :
English
Publisher :
iet
Conference_Titel :
Optical Communications and Networks (ICOCN 2010), 9th International Conference on
Conference_Location :
Nanjing
Type :
conf
DOI :
10.1049/cp.2010.1166
Filename :
5778428
Link To Document :
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