Title :
Clogging failure in microfilter for blood cell separation and its novel improvements
Author :
Dong, Tao ; Yang, Zhaochu ; Egeland, Eirik Bentzen ; Karlsen, Frank ; Jakobsen, Henrik
Author_Institution :
Norwegian Center of Expertise on Micro- & Nanotechnol., Vestfold Univ. Coll., Norway
Abstract :
Clogging failure is common for microfilter utilizing the flat membrane structure. To reduce clogging failure in microfilters, the turbine blade-like micropillar is introduced in microfilter design. Two improved cross-flow microfilter designs employing the blade-like micropillar barrier are presented, one with varied cross-section channels, and the other with Archimedes´ spiral channels. Analogy experimental-data based simulations show that the two aforementioned novel microfilters have good filtrating efficiency and fantastic anti-clogging characteristics. And the commercial value of the turbine blade-like barriers is affirmed by the industry Partners.
Keywords :
bioMEMS; biomembranes; blood; cellular biophysics; microfiltration; separation; anticlogging characteristics; blade-like micropillar barrier; blood cell separation; clogging failure; cross-flow microfilter designs; flat membrane structure; turbine blade-like micropillar; Biomembranes; Cells (biology); Educational institutions; Filters; Filtration; Microfiltration; Nanotechnology; Power engineering; Turbines; White blood cells;
Conference_Titel :
Physical and Failure Analysis of Integrated Circuits, 2009. IPFA 2009. 16th IEEE International Symposium on the
Conference_Location :
Suzhou, Jiangsu
Print_ISBN :
978-1-4244-3911-9
Electronic_ISBN :
1946-1542
DOI :
10.1109/IPFA.2009.5232727