Implementation of on-the-fly scatter correction using dual energy window method in continuous 3D whole body PET scanning

In order to achieve high-throughput and high-sensitivity for whole-body PET studies, the 3D continuous emission and spiral transmission (CEST) scanning are implemented in the PET system, SET-3000 series. In the CEST method, emission and transmission data are acquired simultaneously by moving the patient couch continuously, and were corrected attenuation and rebinned with on-the-fly at each axial sampling. In this work, we describe a solution to scatter correction in which scatter elements are estimated with a hybrid dual energy acquisition combined with hybrid normalize correction. The method estimates trues from an upper energy window through a convolution subtraction following component normalization and self normalization. These processes can be implemented into an on-the-fly reconstruction process. We have applied this "on-the-fly scatter correction" initially to continuous 3D emission data from a 5 ring GSO PET scanner. To investigate the performance, we compared the proposed method with the conventional convolution subtraction. On-the-fly scatter correction scheme had a high performance on continuous 3D whole body emission data