Mesh-based Monte Carlo method for time-gated optical tomography

Author

Chen, Jin ; Intes, Xavier

Author_Institution

Dept. of Biomed. Eng., Rensselaer Polytech. Inst., Troy, NY, USA

fYear

2011

fDate

1-3 April 2011

Firstpage

1

Lastpage

2

Abstract

We describe a novel mesh-based Monte Carlo optical reconstruction algorithm for time-gated 3D optical tomography in small animals. Compared with previous works using voxel-based media discretization, a mesh-based approach is more accurate in modeling targets with curved boundaries or locally refined structures. Using an efficient ray-tracing technique, the mesh-based Monte Carlo method enables us to model both media properties and fluence distribution. Excellent agreement is found when comparing mesh-based MC with 3D voxel-based MC code in a synthetic mouse model.

Keywords

Monte Carlo methods; biomedical optical imaging; image reconstruction; medical image processing; mesh generation; optical tomography; physiological models; ray tracing; 3D voxel-based Monte Carlo code; curved boundaries; fluence distribution; locally refined structures; mesh-based Monte Carlo method; modeling targets; optical reconstruction algorithm; ray tracing; small animal imaging; synthetic mouse model; time-gated optical tomography; voxel-based media discretization; Biomedical optical imaging; Jacobian matrices; Monte Carlo methods; Optical imaging; Optical scattering; Three dimensional displays; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast

Conference_Location

Troy, NY

ISSN

2160-7001

Print_ISBN

978-1-61284-827-3

Type

conf

DOI

10.1109/NEBC.2011.5778559

Filename

5778559