• DocumentCode
    3298087
  • Title

    Ginsenoside-Rg1 does not mitigate the effects of thimerosal on the central nervous system of the pond snail Lymnaea stagnalis

  • Author

    Paradis, Elizabeth ; DiCecco, John

  • Author_Institution
    St. Mary Acad. Bay View, Riverside, RI, USA
  • fYear
    2011
  • fDate
    1-3 April 2011
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    It is well known that certain forms of organic mercury (such as methylmercury) are neurotoxic. In a previous study, we found that the concentration levels at which Thimerosal, an ethylmercury-based preservative found in vaccines, showed neurotoxic effects after soaking for 15 minutes was 100 μM. In this study, we tested the same molar concentration of Thimerosal in the presence of the neuroprotective compound Ginsenoside Rg-1 (Panax ginseng). We found no significant mitigation of the effects of Thimerosal on neuronal function.
  • Keywords
    biomedical engineering; mercury (metal); mercury compounds; neurophysiology; organic compounds; toxicology; Lymnaea stagnalis; Panax ginseng; Thimerosal; central nervous system; ethyl mercury-based preservative; ginsenoside-Rg1; methylmercury; molar concentration; neuronal function; neuroprotective compound; neurotoxic effects; neurotoxicity; organic mercury; pond snail; thimerosal; vaccines; Biomedical engineering; Biomembranes; Central nervous system; Compounds; Microelectrodes; Neurons; Vaccines; Ginseng; Ginsenoside-Rg1; Thimerosal; neuroengineering; neuron; signal processing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast
  • Conference_Location
    Troy, NY
  • ISSN
    2160-7001
  • Print_ISBN
    978-1-61284-827-3
  • Type

    conf

  • DOI
    10.1109/NEBC.2011.5778577
  • Filename
    5778577