A multi-agent system to simulate an apoptosis model of B-CD5 cells

Author

Ballet, P. ; Pers, J.O. ; Rodin, V. ; Tisseau, J.

Author_Institution

Lab. d´´Inf. Ind., Ecole Nat. d´´Ingenieurs de Brest, France

Volume

4

fYear

1998

fDate

11-14 Oct 1998

Firstpage

3799

Abstract

The aim of immune simulations is to reproduce in machina, in vitro and in vivo experimentation. It is then possible to test the cell models and the consequences of their interactions. Thus, by comparing the simulation results with the experimentation results the validity of the model can be demonstrated. A distributed and cooperative system can advantageously be modeled by a multiagent system. With this approach, the abstraction needed to model these phenomena is reduced. The immune system is included in highly cooperative and distributed systems. Moreover, it is quite easy to add or remove entities in the model and to improve their behaviors. In this paper, we present a multiagent system that reproduces in machina a set of in-vitro experimentation on the apoptosis phenomena

Keywords

biocybernetics; multi-agent systems; physiological models; B-CD5 cells; abstraction; apoptosis model; cooperative system; distributed system; immune system; in-vitro experimentation; machina; multiple agent system; Blood; Cells (biology); Immune system; In vitro; Laboratories; Medical simulation; Merging; Multiagent systems;

fLanguage

English

Publisher

ieee

Conference_Titel

Systems, Man, and Cybernetics, 1998. 1998 IEEE International Conference on

Conference_Location

San Diego, CA

ISSN

1062-922X

Print_ISBN

0-7803-4778-1

Type

conf

DOI

10.1109/ICSMC.1998.726679

Filename

726679