Title :
Control of tissue engineered cardiac muscle fibrosis by an endocardial surrogate
Author :
Howell, M.C. ; Masoumi, N. ; Jean, A. ; Engelmayr, G.C., Jr.
Author_Institution :
Dept. of Bioeng., Pennsylvania State Univ., University Park, PA, USA
Abstract :
Here we demonstrate proof-of-concept for controlling cardiac fibroblast collagen secretion on a microfabricated poly(glycerol sebacate) scaffold by endocardial endothelial cells.
Keywords :
biocontrol; biomedical materials; cardiology; cellular biophysics; microfabrication; molecular biophysics; muscle; polymers; proteins; tissue engineering; cardiac fibroblast collagen secretion; endocardial endothelial cells; endocardial surrogate; microfabricated poly(glycerol sebacate) scaffold; tissue engineered cardiac muscle fibrosis; Cardiac tissue; Fibroblasts; Heart; Lasers; Media; Microscopy; Muscles;
Conference_Titel :
Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-61284-827-3
DOI :
10.1109/NEBC.2011.5778663
