Quantitative assessment of macroporous cell scaffold structures using optical coherence tomography (OCT)

Author

Paek, Andrew ; Betz, Martha W. ; Jiang, James ; Cable, Alex ; Fisher, John P. ; Chen, Yu

Author_Institution

Fischell Dept. of Bioeng., Univ. of Maryland, College Park, MD

fYear

2009

fDate

9-10 April 2009

Firstpage

170

Lastpage

172

Abstract

We present the application of optical coherence tomography (OCT) for non-destructive imaging and quantitative characterization of the macroporous cyclic acetal hydrogel cell scaffolds. High-resolution OCT visualizes the microstructures of the tissue engineering scaffolds in three-dimension. The porosity, pore size, and the interconnectivity of the hydrogel scaffolds were characterized quantitatively using OCT.

Keywords

hydrogels; optical tomography; porosity; porous materials; tissue engineering; 3D microstructure; hydrogel cell scaffolds; interconnectivity; macroporous cell scaffold structures; nondestructive imaging; optical coherence tomography; pore size; porosity; quantitative characterization; tissue engineering; Biomedical optical imaging; Coherence; High speed optical techniques; High-resolution imaging; Image segmentation; Microstructure; Optical imaging; Optical interferometry; Optical sensors; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Life Science Systems and Applications Workshop, 2009. LiSSA 2009. IEEE/NIH

Conference_Location

Bethesda, MD

Print_ISBN

978-1-4244-4292-8

Electronic_ISBN

978-1-4244-4293-5

Type

conf

DOI

10.1109/LISSA.2009.4906737

Filename

4906737