Title :
Quantitative assessment of macroporous cell scaffold structures using optical coherence tomography (OCT)
Author :
Paek, Andrew ; Betz, Martha W. ; Jiang, James ; Cable, Alex ; Fisher, John P. ; Chen, Yu
Author_Institution :
Fischell Dept. of Bioeng., Univ. of Maryland, College Park, MD
Abstract :
We present the application of optical coherence tomography (OCT) for non-destructive imaging and quantitative characterization of the macroporous cyclic acetal hydrogel cell scaffolds. High-resolution OCT visualizes the microstructures of the tissue engineering scaffolds in three-dimension. The porosity, pore size, and the interconnectivity of the hydrogel scaffolds were characterized quantitatively using OCT.
Keywords :
hydrogels; optical tomography; porosity; porous materials; tissue engineering; 3D microstructure; hydrogel cell scaffolds; interconnectivity; macroporous cell scaffold structures; nondestructive imaging; optical coherence tomography; pore size; porosity; quantitative characterization; tissue engineering; Biomedical optical imaging; Coherence; High speed optical techniques; High-resolution imaging; Image segmentation; Microstructure; Optical imaging; Optical interferometry; Optical sensors; Tomography;
Conference_Titel :
Life Science Systems and Applications Workshop, 2009. LiSSA 2009. IEEE/NIH
Conference_Location :
Bethesda, MD
Print_ISBN :
978-1-4244-4292-8
Electronic_ISBN :
978-1-4244-4293-5
DOI :
10.1109/LISSA.2009.4906737
