Rheometry of irregularly shaped anisotropic biological samples

Author

Cirka, H.A. ; Farr, W.W. ; Koehler, S.A. ; Billiar, K.L.

Author_Institution

Worcester Polytech. Inst., Worcester, MA, USA

fYear

2011

fDate

1-3 April 2011

Firstpage

1

Lastpage

2

Abstract

Quantification of viscoelastic properties of soft fibrous protein gels and tissue biopsies is vital to the study of disease progression and wound healing, among other research areas. The aim of this work is to establish a method of testing irregularly-shaped and anisotropic biological samples. This method has been tested with samples that have G´ in the range of 10-500 Pa and sizes of approximately 15 mm in diameter. Future aims of this work include characterizing clots from acute stroke patients and studying anisotropic shear in fibrous biopolymer gels.

Keywords

biological tissues; biomechanics; biomedical materials; cellular biophysics; diseases; polymer gels; proteins; viscoelasticity; acute stroke patients; anisotropic shear; disease progression; fibrous biopolymer gels; irregularly shaped anisotropic biological samples; rheometry; soft fibrous protein gels; tissue biopsies; viscoelastic properties; wound healing; Anisotropic magnetoresistance; Geometry; Proteins; Shape; Testing; Torque;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast

Conference_Location

Troy, NY

ISSN

2160-7001

Print_ISBN

978-1-61284-827-3

Type

conf

DOI

10.1109/NEBC.2011.5778710

Filename

5778710