Title :
Surface engineering of functional materials for biosensors
Author :
Vahlberg, C. ; Yazdi, G.R. ; Petoral, R.M., Jr. ; Syväjärvi, M. ; Uvdal, K. ; Spetz, A. Lloyd ; Yakimova, R. ; Khranovsky, V.
Author_Institution :
Dept. of Phys., Biol. & Chem., Linkoping Univ.
fDate :
Oct. 30 2005-Nov. 3 2005
Abstract :
Single crystal SiC with suitable surface termination and ZnO films on top have been grown. Biomolecular immobilization on the grown surfaces has been performed. APTES on Si terminated SiC surfaces and reaction with a compound containing a pre-activated carboxylic group was used. The rate of success for surface functionalization was monitored by XPS. A successful two-step functionalization including binding of MPA through an amide bond formation, between the amine group of APTES and the carboxylic group in MPA on ZnO epilayers, was shown as a proof of concept for biofunctionalization
Keywords :
biosensors; organic compounds; semiconductor thin films; silicon compounds; wide band gap semiconductors; zinc compounds; APTES; MPA; SiC; ZnO; amide bond formation; biomolecular immobilization; biosensors; functional materials; pre-activated carboxylic group; surface engineering; Biological materials; Biosensors; Crystalline materials; Materials science and technology; Semiconductor films; Semiconductor materials; Silicon carbide; Substrates; Surface engineering; Zinc oxide;
Conference_Titel :
Sensors, 2005 IEEE
Conference_Location :
Irvine, CA
Print_ISBN :
0-7803-9056-3
DOI :
10.1109/ICSENS.2005.1597746