Online autocalibration of a PID controller of neuromuscular blockade

Author

Lago, Pedro ; Mendonça, Teresa ; Gonçalves, Lio

Author_Institution

Dept. de Matematica Aplicada, Porto Univ., Portugal

Volume

1

fYear

1998

fDate

1-4 Sep 1998

Firstpage

363

Abstract

A digital PID controller incorporating several modifications to accommodate the characteristics of neuromuscular blockade is described. The control system was evaluated in 30 patients. Subsequent analysis of the data collected during surgery indicates that the variability of the patient responses is much wider than that inferred from the literature. The paper presents an improved empirical model for the pharmacodynamic response to atracurium. Supported on this model, and based on statistical regression techniques, a method for the online tuning of the digital PID controller to the patient´s individual dynamics is presented

Keywords

biocontrol; calibration; digital control; muscle; physiological models; statistical analysis; surgery; three-term control; tuning; atracurium; digital PID controller; neuromuscular blockade; online autocalibration; pharmacodynamic response; statistical regression techniques; surgery; Control systems; Data analysis; Digital control; Drugs; Equations; Muscles; Neuromuscular; Surgery; Switches; Three-term control;

fLanguage

English

Publisher

ieee

Conference_Titel

Control Applications, 1998. Proceedings of the 1998 IEEE International Conference on

Conference_Location

Trieste

Print_ISBN

0-7803-4104-X

Type

conf

DOI

10.1109/CCA.1998.728448

Filename

728448