Aortic pressure with asynchronous ventricular assist

Author

Gu, M. ; Gaumond, R. ; Snyder, A. ; Gardner, J.

Author_Institution

Dept. of Bioeng., Pennsylvania State Univ., University Park, PA, USA

Volume

2

fYear

1999

fDate

36434

Abstract

The authors have examined the relation between Pao (aortic pressure) and parameters of an asynchronous VAD (ventricular assist device) in a lumped-parameter simulation. While left ventricular volume was greater than a threshold level Vth, the 50 ml VAD chamber filled passively at 100 ml/sec. The VAD emptied at a rate of 400 ml/sec when filled. The ventricular elastance (1/C) followed a half-rectified sine waveform. Over a wide range of heart rates determined by Vth, VAD pumping was entrained synchronous to ventricular pumping by this protocol. With the VAD included, Pao(t) waveform complexity increased, with generally more high-frequency signal energy. This has implications for baroreceptor reflex function in VAD patients

Keywords

artificial organs; cardiology; haemodynamics; physiological models; aortic pressure; asynchronous ventricular assist; baroreceptor reflex function; cardiovascular model; half-rectified sine waveform; high-frequency signal energy; left ventricular volume; lumped-parameter simulation; passive chamber filling; ventricular elastance; Baroreflex; Heart rate; Protocols;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.803913

Filename

803913