Title :
Modelling of L-lysine purification process
Author :
Dimitrova, A. ; Georgiev, Tz ; Ratkov, A. ; Ivanova, V. ; Kristeva, J. ; Ratkov, B. ; Mantchev, A.
Author_Institution :
Inst. of Microbiol., Bulgarian Acad. of Sci., Sofia, Bulgaria
Abstract :
Dynamic experimental data of sorption and desorption phase of L-lysine ion-exchange purification process are investigated. The behaviour of the experimental data is described through non-linear dynamic mathematical models, taking into account the relationship between L-lysine concentration and pH of the culture broth, temperature, flow rate, etc. The adequacy of the proposed time series models is confirmed by simulation research.
Keywords :
desorption; ion exchange; molecular biophysics; organic compounds; pH; time series; L-lysine ion-exchange purification; culture broth; desorption; flow rate; modelling; nonlinear dynamic mathematical models; pH; sorption; temperature; time series models; Amino acids; Automation; Difference equations; Feeds; Ionization; Mathematical model; Production; Purification; Resins; Temperature;
Conference_Titel :
Information Technology Interfaces, 2001. ITI 2001. Proceedings of the 23rd International Conference on
Print_ISBN :
953-96769-3-2
DOI :
10.1109/ITI.2001.938036
