A software system for the anatomically constrained reconstruction of conductivity distributions in human body

A software system is introduced, which allows the three dimensional reconstruction of scalar, anisotropic and complex conductivity distributions in human body. Conductivity distributions were determined from a set of applied currents and associated potential measurements. The method bases on the minimization of differences between numerically computed and measured potentials. The computation uses three dimensional conductivity models derived from anatomical models, the anatomical models describe tissue distributions in a region of an individual human body and were created using techniques of digital image processing. The minimization is realized using Powell´s optimization algorithm by variation of tissue specific conductivities starting from an initial guess. Numerical experiments show that the method is capable to assign conductivity values in anatomical models