A new method for assessing volumetric flows in microvascular networks based on laser Doppler and microscopic imagery

Author

Sun, Ying ; Verbeuren, T.J. ; Vallez, Marie O. ; Nilsson, Gert E. ; Sjöberg, Folke

Author_Institution

Dept. of Biomed. Eng., Rhode Island Univ., Kingston, RI, USA

Volume

2

fYear

1999

fDate

36434

Abstract

A new method was developed to produce a composite image of the microvascular network with grayscale proportional to volumetric flow. Velocities in arterioles and venules were assessed with a high resolution laser Doppler imager (LDI). The vascular structures were quantified from the micrograph with a computerized vessel detection algorithm. After registering the vascular network with the LDI scan, volumetric flows were calculated for the entire vasculature. In vivo data were obtained from the hamster cheek pouch in 6 studies

Keywords

Doppler measurement; biomedical imaging; blood flow measurement; blood vessels; haemorheology; image resolution; laser applications in medicine; medical image processing; optical microscopy; arterioles; composite image; computerized vessel detection algorithm; grayscale; hamster cheek pouch; high resolution laser Doppler imager; in vivo data; laser Doppler imagery; microscopic imagery; microvascular networks; vascular structures; venules; volumetric flows; Bifurcation; Biomedical engineering; Biomedical imaging; Detection algorithms; Gray-scale; Image resolution; Intelligent networks; Microscopy; Microwave integrated circuits; Sun;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.804259

Filename

804259