Title :
Modelling electrical activity from cell to body surface
Author :
Buist, M.L. ; Pullan, A.J. ; Hunter, P.J.
Author_Institution :
Dept. of Eng. Sci., Auckland Univ., New Zealand
Abstract :
Presents a modelling framework in which the interaction of the passive external tissue with the extracellular potentials of the myocardium can be studied. The procedure involves iterating between solutions of the bidomain equations, valid in the myocardium, and Laplace´s equation, valid in the passive tissue, until continuity of potential and current flow has been achieved across the heart´s surfaces. Initial simulations on a two-dimensional cross section of a human torso shows that the iterative process readily converges
Keywords :
bioelectric potentials; cardiology; cellular biophysics; iterative methods; muscle; physiological models; Laplace´s equation; body surface; cardiac activation; cardiac electrophysiology; current flow; electrical activity modelling; extracellular potentials; human torso; integrative modelling; iterative process; modelling framework; passive external tissue; two-dimensional cross section; Bioelectric phenomena; Biological system modeling; Electric potential; Extracellular; Heart; Insulation; Iterative methods; Laplace equations; Myocardium; Torso;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804340
